There are usually no symptoms with the first infection with cytomegalovirus. Rarely, reinfection with CMV, or having a weakened immune system, may reactivate the virus and cause symptoms to appear.

When symptoms do appear, they may include

• swollen glands, fatigue, fever, and general weakness
• irritations of the digestive tract, nausea, diarrhea
• jaundice (yellowing of the skin or eyes)

CMV can be very dangerous for people with weakened immune systems. In addition to the symptoms listed above, it can cause blindness and mental disorders.